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Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses

The intestinal tract is in intimate contact with the commensal microflora. Nevertheless, how commensals communicate with cells to ensure immune homeostasis is still unclear. In this study, we found that gut flora DNA (gfDNA) plays a major role in intestinal homeostasis through toll like receptor 9 e...

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Detalhes bibliográficos
Main Authors: Hall, Jason, Bouladoux, Nicolas, Sun, Cheng Ming, Wohlfert, Elizabeth, Blank, Rebecca, Zhu, Qing, Grigg, Michael, Berzofsky, Jay, Belkaid, Yasmine
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712925/
https://ncbi.nlm.nih.gov/pubmed/18835196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.08.009
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