Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses

The intestinal tract is in intimate contact with the commensal microflora. Nevertheless, how commensals communicate with cells to ensure immune homeostasis is still unclear. In this study, we found that gut flora DNA (gfDNA) plays a major role in intestinal homeostasis through toll like receptor 9 e...

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Bibliographic Details
Main Authors: Hall, Jason, Bouladoux, Nicolas, Sun, Cheng Ming, Wohlfert, Elizabeth, Blank, Rebecca, Zhu, Qing, Grigg, Michael, Berzofsky, Jay, Belkaid, Yasmine
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712925/
https://ncbi.nlm.nih.gov/pubmed/18835196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.08.009
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