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Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses

The intestinal tract is in intimate contact with the commensal microflora. Nevertheless, how commensals communicate with cells to ensure immune homeostasis is still unclear. In this study, we found that gut flora DNA (gfDNA) plays a major role in intestinal homeostasis through toll like receptor 9 e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hall, Jason, Bouladoux, Nicolas, Sun, Cheng Ming, Wohlfert, Elizabeth, Blank, Rebecca, Zhu, Qing, Grigg, Michael, Berzofsky, Jay, Belkaid, Yasmine
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712925/
https://ncbi.nlm.nih.gov/pubmed/18835196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.08.009
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