Regulatory T Cells and Human Myeloid Dendritic Cells Promote Tolerance via Programmed Death Ligand-1

Immunotherapy using regulatory T cells (Treg) has been proposed, yet cellular and molecular mechanisms of human Tregs remain incompletely characterized. Here, we demonstrate that human Tregs promote the generation of myeloid dendritic cells (DC) with reduced capacity to stimulate effector T cell res...

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Detalhes bibliográficos
Main Authors: Amarnath, Shoba, Costanzo, Carliann M., Mariotti, Jacopo, Ullman, Jessica L., Telford, William G., Kapoor, Veena, Riley, James L., Levine, Bruce L., June, Carl H., Fong, Timothy, Warner, Noel L., Fowler, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814822/
https://ncbi.nlm.nih.gov/pubmed/20126379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000302
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