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Regulatory T Cells and Human Myeloid Dendritic Cells Promote Tolerance via Programmed Death Ligand-1

Immunotherapy using regulatory T cells (Treg) has been proposed, yet cellular and molecular mechanisms of human Tregs remain incompletely characterized. Here, we demonstrate that human Tregs promote the generation of myeloid dendritic cells (DC) with reduced capacity to stimulate effector T cell res...

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Hlavní autoři: Amarnath, Shoba, Costanzo, Carliann M., Mariotti, Jacopo, Ullman, Jessica L., Telford, William G., Kapoor, Veena, Riley, James L., Levine, Bruce L., June, Carl H., Fong, Timothy, Warner, Noel L., Fowler, Daniel H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814822/
https://ncbi.nlm.nih.gov/pubmed/20126379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000302
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