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Nickel/Bis(oxazoline)-Catalyzed Asymmetric Kumada Reactions of Alkyl Electrophiles: Cross-Couplings of Racemic α-Bromoketones

[Image: see text] The first asymmetric Kumada reactions of alkyl electrophiles are described, specifically, cross-couplings of racemic α-bromoketones with aryl Grignard reagents. Several features of this investigation are of interest. First, the couplings proceed at remarkably low temperature (−40 °...

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Detalhes bibliográficos
Main Authors: Lou, Sha, Fu, Gregory C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814537/
https://ncbi.nlm.nih.gov/pubmed/20050651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909689t
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