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Inner Limiting Membrane Barriers to AAV-mediated Retinal Transduction From the Vitreous

Adeno-associated viral gene therapy has shown great promise in treating retinal disorders, with three promising clinical trials in progress. Numerous adeno-associated virus (AAV) serotypes can infect various cells of the retina when administered subretinally, but the retinal detachment accompanying...

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Detalhes bibliográficos
Main Authors: Dalkara, Deniz, Kolstad, Kathleen D, Caporale, Natalia, Visel, Meike, Klimczak, Ryan R, Schaffer, David V, Flannery, John G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814392/
https://ncbi.nlm.nih.gov/pubmed/19672248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.181
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