Preintegration HIV-1 Inhibition by a Combination Lentiviral Vector Containing a Chimeric TRIM5α Protein, a CCR5 shRNA, and a TAR Decoy

Human immunodeficiency virus (HIV) gene therapy offers a promising alternative approach to current antiretroviral treatments to inhibit HIV-1 infection. Various stages of the HIV life cycle including pre-entry, preintegration, and postintegration can be targeted by gene therapy to block viral infect...

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Detalhes bibliográficos
Main Authors: Anderson, Joseph S, Javien, John, Nolta, Jan A, Bauer, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814390/
https://ncbi.nlm.nih.gov/pubmed/19690520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.187
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