A Fluorescence Polarization Assay for Identifying Ligands that Bind to Vascular Endothelial Growth Factor

Vascular endothelial growth factor (VEGF) is a homodimeric pro-angiogenic protein that induces endothelial cell migration and proliferation primarily through interactions with its major receptors, VEGFR-1 and VEGFR-2. Inhibitors of one or both of these VEGF-receptor interactions could be beneficial...

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Bibliografiske detaljer
Main Authors: Peterson, Kimberly J., Sadowsky, Jack D., Scheef, Elizabeth A., Pal, Soumen, Kourentzi, Katerina D., Willson, Richard C., Bresnick, Emery H., Sheibani, Nader, Gellman, Samuel H.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814342/
https://ncbi.nlm.nih.gov/pubmed/18413228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.03.043
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