Loading...

Novel CD8(+) Treg suppress EAE by TGF-β- and IFN-γ-dependent mechanisms

Although CD8(+) Treg-mediated suppression has been described, CD8(+) Treg remain poorly characterized. Here we identify a novel subset of CD8(+) Treg that express latency-associated peptide (LAP) on their cell surface (CD8(+)LAP(+) cells) and exhibit regulatory activity in vitro and in vivo. Only a...

Full description

Saved in:
Bibliographic Details
Main Authors: Chen, Mei-Ling, Yan, Bo-Shiun, Kozoriz, Deneen, Weiner, Howard L.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814307/
https://ncbi.nlm.nih.gov/pubmed/19768696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939441
Tags: Add Tag
No Tags, Be the first to tag this record!