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CBD Suppression of EAE is Correlated with Early Inhibition of Splenic IFN-γ+CD8+ T Cells and Modest Inhibition of Neuroinflammation

In this study cannabidiol (CBD) was administered orally to determine its effects and mechanisms in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS). We hypothesized that 75mg/kg of oral CBD given for 5 days after initiation of disease would reduce EAE severity thr...

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Detalhes bibliográficos
Publicado no:J Neuroimmune Pharmacol
Main Authors: Nichols, James M., Kummari, Evangel, Sherman, Jessica, Yang, Eun-Ju, Dhital, Saphala, Gilfeather, Christa, Yray, Gabriella, Morgan, Timothy, Kaplan, Barbara L. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679272/
https://ncbi.nlm.nih.gov/pubmed/32440886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-020-09917-8
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