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Accessibility of the CLC-0 Pore to Charged Methanethiosulfonate Reagents

Using the substituted-cysteine-accessibility method, we previously showed that a cysteine residue introduced to the Y512 position of CLC-0 was more rapidly modified by a negatively charged methanethiosulfonate (MTS) reagent, 2-sulfonatoethyl MTS (MTSES), than by the positively charged 2-(trimethylam...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Dong, Yu, Wei-Ping, Chen, Tsung-Yu
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814198/
https://ncbi.nlm.nih.gov/pubmed/20141750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.066
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