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The hemopexin domain of MMP-9 inhibits angiogenesis and retards the growth of intracranial glioblastoma xenograft in nude mice
Matrix Metalloproteinase-9 (MMP-9) consists of a prodomain, catalytic domain with three fibronectin-like type II modules and C-terminal hemopexin-like (PEX) domain. These domains play distinct roles in terms of proteolytic activity, substrate binding and interaction with inhibitors and receptors. In...
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Principais autores: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814063/ https://ncbi.nlm.nih.gov/pubmed/18942717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23951 |
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