Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival

BACKGROUND: Collagen and calcium-binding EGF domains 1 (CCBE1) is an uncharacterised gene that has down-regulated expression in breast cancer. As CCBE1 maps to 18q21.32, a region frequently exhibiting loss of heterozygosity in ovarian cancer, the aim of this study was to determine the expression and...

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Bibliografiske detaljer
Main Authors:	Barton, C A, Gloss, B S, Qu, W, Statham, A L, Hacker, N F, Sutherland, R L, Clark, S J, O'Brien, P M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2010
Fag:	Clinical Study
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2813742/ https://ncbi.nlm.nih.gov/pubmed/19935792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605429
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Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival

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