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Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution
To explore the mechanisms and evolution of cell-cycle control, we analyzed the position and conservation of large numbers of phosphorylation sites for the cyclin-dependent kinase Cdk1 in the budding yeast Saccharomyces cerevisiae. We combined specific chemical inhibition of Cdk1 with quantitative ma...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813701/ https://ncbi.nlm.nih.gov/pubmed/19779198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1172867 |
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