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Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading

The origin recognition complex (ORC) is an essential DNA replication initiation factor conserved in all eukaryotes. In Saccharomyces cerevisiae, ORC binds to specific DNA elements; however, in higher eukaryotes, ORC exhibits little sequence specificity in vitro or in vivo. We investigated the genome...

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Bibliografische gegevens
Hoofdauteurs: MacAlpine, Heather K., Gordân, Raluca, Powell, Sara K., Hartemink, Alexander J., MacAlpine, David M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813476/
https://ncbi.nlm.nih.gov/pubmed/19996087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.097873.109
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