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ANP attenuates inflammatory signaling and Rho pathway of lung endothelial permeability induced by LPS and TNFα

We have previously reported protective effects of atrial natriuretic peptide (ANP) against endothelial cell (EC) permeability induced by thrombin via suppression of Rho GTPase pathway of barrier dysfunction by protein kinase A and Epac-Rap1-Tiam1-Rac signaling cascades. This study tested effects of...

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Detalhes bibliográficos
Main Authors: Xing, Junjie, Birukova, Anna A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813389/
https://ncbi.nlm.nih.gov/pubmed/19931545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2009.11.006
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