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Atrial natriuretic peptide attenuates LPS-induced lung vascular leak: role of PAK1

Increased levels of atrial natriuretic peptide (ANP) in the models of sepsis, pulmonary edema, and acute respiratory distress syndrome (ARDS) suggest its potential role in the modulation of acute lung injury. We have recently described ANP-protective effects against thrombin-induced barrier dysfunct...

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Autors principals: Birukova, Anna A., Xing, Junjie, Fu, Panfeng, Yakubov, Bakhtiyor, Dubrovskyi, Oleksii, Fortune, Jennifer A., Klibanov, Alexander M., Birukov, Konstantin G.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980395/
https://ncbi.nlm.nih.gov/pubmed/20729389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00202.2009
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