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Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation
BACKGROUND: Mutations in multiple genes have been implicated in familial atrial fibrillation (AF), but the underlying mechanisms, and thus implications for therapy, remain ill-defined. METHODS AND RESULTS: Among 231 participants in the Vanderbilt AF Registry, we found a mutation in KCNQ1 (encoding t...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813326/ https://ncbi.nlm.nih.gov/pubmed/19646991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.07.020 |
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