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Metabotropic Glutamate 5 Receptor (mGluR5) Antagonists Decrease Nicotine Seeking, But Do Not Affect the Reinforcement Enhancing Effects of Nicotine

Nicotine self-administration models typically evaluate the effects of smoking cessation aides on ‘primary reinforcement’ engendered by nicotine. However, the more recently described reinforcement enhancing effects of the drug are not always included in experimental analyses of potential therapeutics...

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Detalhes bibliográficos
Main Authors: Palmatier, Matthew I, Liu, Xiu, Donny, Eric C, Caggiula, Anthony R, Sved, Alan F
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812904/
https://ncbi.nlm.nih.gov/pubmed/18046312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301623
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