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Metabotropic Glutamate 5 Receptor (mGluR5) Antagonists Decrease Nicotine Seeking, But Do Not Affect the Reinforcement Enhancing Effects of Nicotine

Nicotine self-administration models typically evaluate the effects of smoking cessation aides on ‘primary reinforcement’ engendered by nicotine. However, the more recently described reinforcement enhancing effects of the drug are not always included in experimental analyses of potential therapeutics...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Palmatier, Matthew I, Liu, Xiu, Donny, Eric C, Caggiula, Anthony R, Sved, Alan F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812904/
https://ncbi.nlm.nih.gov/pubmed/18046312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301623
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