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Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis

We describe the application of a novel screening approach that combines automated yeast genetics, synthetic genetic array (SGA) analysis, and a high-content screening (HCS) system to examine mitotic spindle morphogenesis. We measured numerous spindle and cellular morphological parameters in thousand...

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Xehetasun bibliografikoak
Egile Nagusiak: Vizeacoumar, Franco J., van Dyk, Nydia, S.Vizeacoumar, Frederick, Cheung, Vincent, Li, Jingjing, Sydorskyy, Yaroslav, Case, Nicolle, Li, Zhijian, Datti, Alessandro, Nislow, Corey, Raught, Brian, Zhang, Zhaolei, Frey, Brendan, Bloom, Kerry, Boone, Charles, Andrews, Brenda J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812844/
https://ncbi.nlm.nih.gov/pubmed/20065090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200909013
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