Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis

We describe the application of a novel screening approach that combines automated yeast genetics, synthetic genetic array (SGA) analysis, and a high-content screening (HCS) system to examine mitotic spindle morphogenesis. We measured numerous spindle and cellular morphological parameters in thousand...

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Detaylı Bibliyografya
Asıl Yazarlar: Vizeacoumar, Franco J., van Dyk, Nydia, S.Vizeacoumar, Frederick, Cheung, Vincent, Li, Jingjing, Sydorskyy, Yaroslav, Case, Nicolle, Li, Zhijian, Datti, Alessandro, Nislow, Corey, Raught, Brian, Zhang, Zhaolei, Frey, Brendan, Bloom, Kerry, Boone, Charles, Andrews, Brenda J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2010
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812844/
https://ncbi.nlm.nih.gov/pubmed/20065090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200909013
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