Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis

We describe the application of a novel screening approach that combines automated yeast genetics, synthetic genetic array (SGA) analysis, and a high-content screening (HCS) system to examine mitotic spindle morphogenesis. We measured numerous spindle and cellular morphological parameters in thousand...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Vizeacoumar, Franco J., van Dyk, Nydia, S.Vizeacoumar, Frederick, Cheung, Vincent, Li, Jingjing, Sydorskyy, Yaroslav, Case, Nicolle, Li, Zhijian, Datti, Alessandro, Nislow, Corey, Raught, Brian, Zhang, Zhaolei, Frey, Brendan, Bloom, Kerry, Boone, Charles, Andrews, Brenda J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Rockefeller University Press 2010
Θέματα:
Research Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812844/
https://ncbi.nlm.nih.gov/pubmed/20065090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200909013
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