Neuropilin-2 mediates VEGF-C–induced lymphatic sprouting together with VEGFR3

Vascular sprouting is a key process-driving development of the vascular system. In this study, we show that neuropilin-2 (Nrp2), a transmembrane receptor for the lymphangiogenic vascular endothelial growth factor C (VEGF-C), plays an important role in lymphatic vessel sprouting. Blocking VEGF-C bind...

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Detalhes bibliográficos
Main Authors: Xu, Yunling, Yuan, Li, Mak, Judy, Pardanaud, Luc, Caunt, Maresa, Kasman, Ian, Larrivée, Bruno, del Toro, Raquel, Suchting, Steven, Medvinsky, Alexander, Silva, Jillian, Yang, Jian, Thomas, Jean-Léon, Koch, Alexander W., Alitalo, Kari, Eichmann, Anne, Bagri, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812843/
https://ncbi.nlm.nih.gov/pubmed/20065093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200903137
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