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Fungal echinocandin resistance
The echinocandins are the newest class of antifungal agents in the clinical armory. These secondary metabolites are non-competitive inhibitors of the synthesis of β-(1,3)-glucan, a major structural component of the fungal cell wall. Recent work has shown that spontaneous mutations can arise in two h...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Academic Press
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812698/ https://ncbi.nlm.nih.gov/pubmed/19770064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fgb.2009.09.003 |
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