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Fungal echinocandin resistance

The echinocandins are the newest class of antifungal agents in the clinical armory. These secondary metabolites are non-competitive inhibitors of the synthesis of β-(1,3)-glucan, a major structural component of the fungal cell wall. Recent work has shown that spontaneous mutations can arise in two h...

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Detalhes bibliográficos
Main Authors: Walker, Louise A., Gow, Neil A.R., Munro, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812698/
https://ncbi.nlm.nih.gov/pubmed/19770064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fgb.2009.09.003
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