Facile Construction of Fluorescent Peptide Microarrays: One-Step Fluorescent Derivatization of Sub-microscale Peptide Aldehydes for Selective Terminal Immobilization

In this note, we demonstrate the utility of bifunctional fluorescent linkers to facilitate the construction of peptide microarrays with either an N or C-terminal alkylamine for directionally preferred peptide immobilization. Significantly, these small tags facilitate HPLC profiling, while limiting i...

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Hauptverfasser: Dong, He, Song, Xuezheng, Lasanajak, Yi, Cummings, Richard D., Chaikof, Elliot L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812691/
https://ncbi.nlm.nih.gov/pubmed/19903446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.11.001
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