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Preparation of a mannose-6-phosphate glycan microarray through fluorescent derivatization, phosphorylation, and immobilization of natural high-mannose N-glycans and its application in ligand identification of P-type lectins

Glycan microarrays prepared by immobilization of amino-functionalized glycans on NHS-activated glass slides have been successfully used to study protein-glycan interactions. Fluorescently tagged glycans with an amino functional group can be prepared from natural glycans released from glycoproteins....

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Song, Xuezheng, Heimburg-Molinaro, Jamie, Dahms, Nancy M., Smith, David F., Cummings, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668285/
https://ncbi.nlm.nih.gov/pubmed/22057522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-373-8_9
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