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Production and sorting of transgenic, modified human parathyroid hormone in vivo in rat salivary glands

Polarized salivary epithelial cells can sort secretory proteins towards either the basolateral or apical pole. Transgenic human parathyroid hormone (hPTH) exclusively sorts apically in rat submandibular glands. To help understand this specific process we modified the hPTH cDNA sequence and delivered...

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Detalles Bibliográficos
Main Authors: Adriaansen, Janik, Zheng, Changyu, Perez, Paola, Baum, Bruce J.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812688/
https://ncbi.nlm.nih.gov/pubmed/19944067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.11.135
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