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Production and sorting of transgenic, modified human parathyroid hormone in vivo in rat salivary glands

Polarized salivary epithelial cells can sort secretory proteins towards either the basolateral or apical pole. Transgenic human parathyroid hormone (hPTH) exclusively sorts apically in rat submandibular glands. To help understand this specific process we modified the hPTH cDNA sequence and delivered...

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Detalhes bibliográficos
Main Authors: Adriaansen, Janik, Zheng, Changyu, Perez, Paola, Baum, Bruce J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812688/
https://ncbi.nlm.nih.gov/pubmed/19944067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.11.135
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