Impaired Methylation As A Novel Mechanism for Proteasome Suppression In Liver Cells

The proteasome is a multi-catalytic protein degradation enzyme that is regulated by ethanol-induced oxidative stress; such suppression is attributed to CYP2E1-generated metabolites. However, under certain conditions, it appears that in addition to oxidative stress, other mechanisms are also involved...

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Bibliografiske detaljer
Main Authors: Osna, Natalia A., White, Ronda L., Donohue, Terrence M., Beard, Michael, Tuma, Dean J., Kharbanda, Kusum K.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812660/
https://ncbi.nlm.nih.gov/pubmed/20026058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.12.074
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