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Intrinsic hTRF1fluorescence quenching reveals details of telomere DNA binding activity: Impact of DNA length, structure and position of telomeric repeats

The myb-DNA binding domain is characterized by a 3-alpha helical bundle and three repeats of this domain drive sequence specific DNA-binding of the c-myb transcription factor. Human TRF1 contains a single myb-related domain and as a homodimer, enables the sequence specific binding of telomeric DNA....

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Autori principali: Tahmaseb, Kambiz, Turchi, John J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812646/
https://ncbi.nlm.nih.gov/pubmed/19887064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.10.015
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