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ICOS promotes IL-17 synthesis in colonic intraepithelial lymphocytes in IL-10(−/−) mice
In the absence of IL-10, colonic inflammation ensues, which is characterized by high levels of IL-17. Here, we demonstrate a direct correlation between ICOS expression and IL-17 production in cIELs. IL-10(−/−) mice had increased numbers of cIELs and greater colon weight. Although the CD69 early acti...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Society for Leukocyte Biology
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812556/ https://ncbi.nlm.nih.gov/pubmed/19889730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0409238 |
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