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Fluorescent Molecular Rotors as Dyes to Characterize Polysorbate-Containing IgG Formulations

PURPOSE: The aim was to evaluate fluorescent molecular rotors (DCVJ and CCVJ), which are mainly sensitive to viscosity, for the characterization of polysorbate-containing IgG formulations and compare them to the polarity-sensitive dyes ANS, Bis-ANS and Nile Red. METHODS: IgG formulations with polyso...

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Detalhes bibliográficos
Main Authors: Hawe, Andrea, Filipe, Vasco, Jiskoot, Wim
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812426/
https://ncbi.nlm.nih.gov/pubmed/20041280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-0020-2
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