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Fluorescence Single Particle Tracking for the Characterization of Submicron Protein Aggregates in Biological Fluids and Complex Formulations

PURPOSE: To evaluate the potential of fluorescence single particle tracking (fSPT) for the characterization of submicron protein aggregates in human serum, plasma and formulations containing human serum albumin (HSA). METHODS: A monoclonal IgG was covalently labeled with a fluorescent dye and cross-...

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Detalhes bibliográficos
Main Authors: Filipe, Vasco, Poole, Robert, Kutscher, Marika, Forier, Katrien, Braeckmans, Kevin, Jiskoot, Wim
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073042/
https://ncbi.nlm.nih.gov/pubmed/21298328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0374-0
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