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The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity and Transmissibility in Ducks

While the molecular mechanism of membrane fusion by the influenza virus hemagglutinin (HA) protein has been studied extensively in vitro, the role of acid-dependent HA protein activation in virus replication, pathogenesis, and transmission in vivo has not been characterized. To investigate the biolo...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Reed, Mark L., Bridges, Olga A., Seiler, Patrick, Kim, Jeong-Ki, Yen, Hui-Ling, Salomon, Rachelle, Govorkova, Elena A., Webster, Robert G., Russell, Charles J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology (ASM) 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812356/
https://ncbi.nlm.nih.gov/pubmed/19923184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02069-09
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