Synthetic β-(1→6)-Linked N-Acetylated and Nonacetylated Oligoglucosamines Used To Produce Conjugate Vaccines for Bacterial Pathogens

Vaccines for pathogens usually target strain-specific surface antigens or toxins, and rarely is there broad antigenic specificity extending across multiple species. Protective antibodies for bacteria are usually specific for surface or capsular antigens. β-(1→6)-Poly-N-acetyl-d-glucosamine (PNAG) is...

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Bibliographische Detailangaben
Hauptverfasser: Gening, Marina L., Maira-Litrán, Tomás, Kropec, Andrea, Skurnik, David, Grout, Martha, Tsvetkov, Yury E., Nifantiev, Nikolay E., Pier, Gerald B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812210/
https://ncbi.nlm.nih.gov/pubmed/19948836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01093-09
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