Comparative Opsonic and Protective Activities of Staphylococcus aureus Conjugate Vaccines Containing Native or Deacetylated Staphylococcal Poly-N-Acetyl-β-(1-6)-Glucosamine

Staphylococcus aureus and Staphylococcus epidermidis both synthesize the surface polysaccharide poly-N-acetyl-β-(1-6)-glucosamine (PNAG), which is produced in vitro with a high level (>90%) of the amino groups substituted by acetate. Here, we examined the role of the acetate substituents of PNAG...

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Bibliografiske detaljer
Main Authors: Maira-Litrán, Tomás, Kropec, Andrea, Goldmann, Donald A., Pier, Gerald B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230901/
https://ncbi.nlm.nih.gov/pubmed/16177353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6752-6762.2005
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