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Murine Model of a Disseminated Infection by the Novel Fungus Fonsecaea monophora and Successful Treatment with Posaconazole

We have evaluated the efficacy of posaconazole, amphotericin B, and itraconazole in a murine model of disseminated infection by Fonsecaea monophora. Of these three antifungal drugs tested, posaconazole prolonged survival significantly and reduced the fungal load in most of the organs tested. Bioassa...

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Autors principals: Calvo, Enrique, Pastor, F. Javier, Rodríguez, M. Mar, Mayayo, Emilio, Salas, Valentina, Guarro, Josep
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812182/
https://ncbi.nlm.nih.gov/pubmed/20008773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01284-09
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