Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia

INTRODUCTION: Aminoglycosides aerosolization might achieve better diffusion into the alveolar compartment than intravenous use. The objective of this multicenter study was to evaluate aerosol-delivered amikacin penetration into the alveolar epithelial lining fluid (ELF) using a new vibrating mesh ne...

Full description

Saved in:
Bibliographic Details
Main Authors: Luyt, Charles-Edouard, Clavel, Marc, Guntupalli, Kalpalatha, Johannigman, Jay, Kennedy, John I, Wood, Christopher, Corkery, Kevin, Gribben, Dennis, Chastre, Jean
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811890/
https://ncbi.nlm.nih.gov/pubmed/20003269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8206
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items