NKTR-061 (inhaled amikacin) delivers high lung doses in mechanically ventilated patients with pneumonia and in healthy subjects

Eitemau Tebyg

• Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia
  gan: Luyt, Charles-Edouard, et al.
  Cyhoeddwyd: (2009)
• High epithelial lining fluid concentrations of NKTR-061 (inhaled amikacin) twice daily achieved in pneumonic portions of lung
  gan: Chastre, J, et al.
  Cyhoeddwyd: (2008)
• Decrease in intravenous antibiotic use with adjunctive aerosolized amikacin treatment in intubated mechanically ventilated patients with Gram-negative pneumonia
  gan: Niederman, M, et al.
  Cyhoeddwyd: (2007)
• Inhaled ceftazidime and amikacin versus inhaled colistin in the treatment of gram negative ventilator associated pneumonia
  gan: Nassar, YS, et al.
  Cyhoeddwyd: (2015)
• Performance of amikacin inhale: impact of supplemental oxygen and device orientation
  gan: Kadrichu, N, et al.
  Cyhoeddwyd: (2015)