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Detecting rare variants for complex traits using family and unrelated data

Large genome-wide association studies have been performed to detect common genetic variants involved in common diseases, but most of the variants found this way account for only a small portion of the trait variance. Furthermore, candidate gene based resequencing suggests that many rare genetic vari...

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Detalhes bibliográficos
Main Authors: Zhu, Xiaofeng, Feng, Tao, Li, Yali, Lu, Qing, Elston, Robert C
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811752/
https://ncbi.nlm.nih.gov/pubmed/19847924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20449
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