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Genome-wide searching of rare genetic variants in WTCCC data

Although they have demonstrated success in searching for common variants for complex diseases, Genome-Wide Association (GWA) studies are less successful in detecting rare genetic variants because of the poor statistical power of most of current methods. We developed a two-stage method that can apply...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Feng, Tao, Zhu, Xiaofeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922446/
https://ncbi.nlm.nih.gov/pubmed/20549515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-010-0849-9
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