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A novel method to detect rare variants using both family and unrelated case-control data

To detect rare variants associated with a phenotype, we develop a novel statistical method that can use both family and unrelated case-control data. Unlike the currently existing methods, we first use family data to calculate weights to be given to rare variants, differentiating between concordantly...

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מידע ביבליוגרפי
Main Authors: Feng, Tao, Elston, Robert C, Zhu, Xiaofeng
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287921/
https://ncbi.nlm.nih.gov/pubmed/22373319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S80
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