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Enzymatic and nonenzymatic functions of viral RNA-dependent RNA polymerases within oligomeric arrays

Few antivirals are effective against positive-strand RNA viruses, primarily because the high error rate during replication of these viruses leads to the rapid development of drug resistance. One of the favored current targets for the development of antiviral compounds is the active site of viral RNA...

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Detalhes bibliográficos
Main Authors: Spagnolo, Jeannie F., Rossignol, Evan, Bullitt, Esther, Kirkegaard, Karla
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811667/
https://ncbi.nlm.nih.gov/pubmed/20051491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1955410
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