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Comparison of Two Pharmacodynamic Transduction Models for the Analysis of Tumor Therapeutic Responses in Model Systems

Semi-mechanistic pharmacodynamic (PD) models that capture tumor responses to anticancer agents with fidelity can provide valuable insights that could aid in the optimization of dosing regimens and the development of drug delivery strategies. This study evaluated the utility and potential interchange...

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Detalhes bibliográficos
Main Authors: Yang, Jun, Mager, Donald E., Straubinger, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811636/
https://ncbi.nlm.nih.gov/pubmed/19902363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9155-7
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