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Pharmacodynamic modeling of synergistic birinapant/paclitaxel interactions in pancreatic cancer cells
BACKGROUND: For most patients, pancreatic adenocarcinoma responds poorly to treatment, and novel therapeutic approaches are needed. Standard-of-care paclitaxel (PTX), combined with birinapant (BRP), a bivalent mimetic of the apoptosis antagonist SMAC (second mitochondria-derived activator of caspase...
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| Veröffentlicht in: | BMC Cancer |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7583190/ https://ncbi.nlm.nih.gov/pubmed/33097020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07398-9 |
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