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Restricted Autoantigen Recognition Associated With Deletional and Adaptive Regulatory Mechanisms

Autoimmune diabetes (T1D) is characterized by CD4+ T cell reactivity to a variety of islet-associated antigens. At-risk individuals, genetically predisposed to T1D, often have similar T cell reactivity, but nevertheless fail to progress to clinically overt disease. In order to study the immune toler...

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Bibliografische gegevens
Hoofdauteurs: Gebe, John A., Yue, Betty B., Unrath, Kelly A, Falk, Ben A., Nepom, Gerald T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811410/
https://ncbi.nlm.nih.gov/pubmed/19535636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804046
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