Global Regulator SATB1 Recruits β-Catenin and Regulates T(H)2 Differentiation in Wnt-Dependent Manner

In vertebrates, the conserved Wnt signalling cascade promotes the stabilization and nuclear accumulation of β-catenin, which then associates with the lymphoid enhancer factor/T cell factor proteins (LEF/TCFs) to activate target genes. Wnt/β -catenin signalling is essential for T cell development and...

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Hauptverfasser: Notani, Dimple, Gottimukkala, Kamalvishnu P., Jayani, Ranveer S., Limaye, Amita S., Damle, Madhujit V., Mehta, Sameet, Purbey, Prabhat Kumar, Joseph, Jomon, Galande, Sanjeev
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811152/
https://ncbi.nlm.nih.gov/pubmed/20126258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000296
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