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Global Regulator SATB1 Recruits β-Catenin and Regulates T(H)2 Differentiation in Wnt-Dependent Manner
In vertebrates, the conserved Wnt signalling cascade promotes the stabilization and nuclear accumulation of β-catenin, which then associates with the lymphoid enhancer factor/T cell factor proteins (LEF/TCFs) to activate target genes. Wnt/β -catenin signalling is essential for T cell development and...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811152/ https://ncbi.nlm.nih.gov/pubmed/20126258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000296 |
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