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Correcting for gene-specific dye bias in DNA microarrays using the method of maximum likelihood
MOTIVATION: In two-color microarray experiments, well-known differences exist in the labeling and hybridization efficiency of Cy3 and Cy5 dyes. Previous reports have revealed that these differences can vary on a gene-by-gene basis, an effect termed gene-specific dye bias. If uncorrected, this bias c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811084/ https://ncbi.nlm.nih.gov/pubmed/17623705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btm347 |
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