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Bias correction for estimated QTL effects using the penalized maximum likelihood method
A penalized maximum likelihood method has been proposed as an important approach to the detection of epistatic quantitative trait loci (QTL). However, this approach is not optimal in two special situations: (1) closely linked QTL with effects in opposite directions and (2) small-effect QTL, because...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3313049/ https://ncbi.nlm.nih.gov/pubmed/21934700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2011.86 |
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